Get's Vaccines: New Hope People with Breast Cancer

Experts from the University of Arkansas Medical Sciences starts clinical trial of a vaccine to prevent recurrence of breast cancer.
According to Laura Hutchins, director of hematology and oncology, who was also the leader of the research, if successful, this vaccine is not to traditional treatments such as chemotherapy and radiation therapy to replace, but are used as additional treatment for patients.
Thomas Kieber-Emmons has been developed, director of basic research of breast cancer in the UAMS Winthrop P. Rockefeller Cancer Institute, said the vaccine under study, more than a decade studying the immune system. He said the most important key is to understand how the different molecules together to eradicate the disease.
cells of breast cancer is known by molecules such as antigens, which focused on the production of antibodies that breast cancer cells can trigger the fight works. However, do not stimulate carbohydrate antigens on cancer cells, a strong immune response.
Kieber-Emmons and his team have found another approach. They developed a peptide antigen (peptide-antigen) which is similar to the carbohydrate.
This peptide is a compound of two or more amino acids. basic peptide vaccines with this thing the body produces antibodies with a target peptide in vaccines and carbohydrates, they produce copies in the cells of breast cancer.
The experiments were conducted in several stages. The first step for a period of 4-6 months, and women involved in malignant breast cancer and women with cancer that has returned to the reduction of symptoms experienced. These women received 5 doses of vaccine.
Phase 2 instead of 1 year and women who participated in breast cancer and no symptoms, but for breast cancer in high risk returned. This woman has stopped chemotherapy for at least 6 months. The number of patients included in this study has not been determined.
Breast cancer is the leading cause of death among Hispanic women and the No. 2 cause of death among white women, black and Asian women and American Indians. In 2004 40.954 women died of breast cancer.

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Cough Medicines vs. Cancer

Netherlands - Health experts at the Erasmus Medical Center in the Netherlands found the composition of the cough suppressant, dextromethorphan, could the level of metabolism of tamoxifen is used to treat breast cancer detect. The results show indirectly the effectiveness of the treatment on their own, more effective and reduce side effects.

Tamoxifen for the treatment and prevention of breast cancer is metabolized by the body in endoxifen. Endoxifen cancer drugs work and affect the patient consumes. Two enzymes in the body metabolize CYP2D6 and CYP3A, tamoxifen and endoxifen and destroy cancer cells.

"Well, all patients (breast cancer) in the Netherlands with dextromethorphan were at a dose of 20 mg treated to 40 mg. The composition is capable metabolism tamoxifen within three weeks, " said Anne-Joy de Graan, doctors at the Health Department Erasmus Medical Centre, Netherlands.

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Cuba Find Lung Cancer Vaccine

Cuba - Vaccines lung cancer was found by the National Coordination Center for Clinical Trials Cuba. This vaccine is reserved for patients with lung cancer progressed.

Pedro Pablo Guerra tells a researcher that this drug one of the hopes of the Cuban Ministry of Health, is addressed to patients in need.

"These drugs are immunogenic, which was from the Center for Molecular Immunology (CMI) is developed, in the fourth stage of the phase of clinical trials. This to be effective and to improve the quality of life of patients with proven lung cancer, " said an expert.

Guerra said that this vaccine was stage clinical studies in hospitals and sometimes as a product that was recognized in several countries are registered.

The vaccine, called CIMAVAX EGF was presented at the Fourth International Congress of Pharmacology in Havana. More than 450 experts from Brazil, Indonesia, Spain, the United States, Japan, Cuba and other countries participated.

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Soybean | Prevent Breast Cancer Recurrence

Soybeans, which became the basis of some food ingredients such as soy sauce, tofu, and demonstrated the possibility of returning cancer cells, in particular, to prevent breast cancer.

Soy isoflavones have a similar chemical structure to estrogen, so it can act like estrogen in the body tissue. The number of people who consume soy isoflavones in soy products has increased recently. And there was concern about the effects of soy consumption on estrogen and progesterone early receptor-positive cancer of the breast in women due to the development of tumors depend on estrogen.

In a study in Cancer Hospital of the University of Medical Sciences of Harbin in China, the scientists involved 524 women undergoing cancer 5-6 years earlier. For lack of understanding of the effects of soy isoflavones in patients with breast cancer adjuvant endocrine therapy, scientists try to find out through this research.

"In the postmenopausal patients when combined with the lowest soy intake (less than 15.2 mg / day) in comparison, are often of soybeans (more than 42.3 mg / day) seems to be at low risk of disease have experienced more back, "said Dr. Qingyan. Zhang.

"The rate of recurrence of breast cancer, estrogen and progesterone-positive PC 12.9 lower compared with patients with high intake of soy isoflavones with 18.7 pc of inclusion is low," he said.

But overall there was no effect on survival in postmenopausal women and no relationship between soy intake and survival in postmenopausal women.

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